OncoBriefs - Oncology Research News

April 2026 (177)

• Neoadjuvant and Adjuvant Nivolumab with IRE for Liver Cancer
• IL15-CIK Cells: When Your Immune System Gets a Startup-Style Upgrade
• Nationwide Mammographic Screening Among Transgender and Gender Diverse Individuals
• Protein Makeovers: How a Molecular Stylist Keeps Your Immune Cells Camera-Ready
• Breast Cancer Mortality: The National Average Is Lying to You
• Synthetic Super-Enhancers: Tricking Brain Cancer Into Destroying Itself
• BULLETIN: Tiny Silicon Cages Now Moonlighting as Fake Enzymes That Kill Cancer Cells
• The Verdict on Tumor Volume: Can a 3-Month PET Scan Predict Who Survives Advanced Prostate Cancer?
• Neoadjuvant Chemotherapy With CAPOX vs. Chemoradiation for Rectal Cancer (CONVERT Trial)
• Igniting Endogenous Calcipoptosis via ER-Mitochondrial Calcium Shuttle Hijacking
• Colon Cancer's Spell-Check System is Broken, and That's Actually Good News
• Pancreatic Cancer Has a Bouncer Problem
• Pembrolizumab + Chemoradiation for Bladder-Sparing Cancer Treatment
• MicroRNAs in Oncology: Tiny Molecules, Big Promises, and an AI Auctioneer
• A Brief Timeline of Humans Asking Robots to Stare at Their Colons
• The Blood Test Boss Fight: How a Swedish Team Built a Multi-Cancer Cheat Code from Proteins and Metabolites
• The Sugar-Coated Escape Artist
• The Glow-Up That Keeps on Giving
• Your Thymus: The Tiny Organ That Got Dumped by Medicine (And Wants You Back)
• Your Immune System's Pac-Man Just Got a Serious Upgrade
• The Verdict Is In on Elranatamab—But the Jury's Still Deliberating
• The Battle Against a Stubborn Gut Invader Just Got More Complicated
• When Lung Cancer Surgeons Finally Agree on the Rules of the Game
• When a Virus Crashes the Tumor Party: How IN-DEPTH Reveals Cancer's Hidden Social Networks
• The Great Amino Acid Heist: How Brain Tumors Rob Your Immune System Blind
• When Your Inbox Saves Your Life: Digital Health Goes After Lung Cancer
• CAR T Cell Therapy in Kids: The Heroes, Villains, and Plot Twists
• Your Bile Ducts Have Secrets, and Genetic Testing Just Became the Ultimate Gossip
• Math problem: 24 × 1 = a cure?
• When "Standard of Care" Isn't Caring Enough: A New Hope for Metastatic Colorectal Cancer
• When Light Therapy Hits a Wall (and How Scientists Blew Right Through It)
• Going Once, Going Twice: Sold to the Red Blood Cell Carrying Cancer-Fighting Instructions
• Radiation Therapy Has Been Doing Immunotherapy's Job This Whole Time - We Just Didn't Notice
• Your Brain's Worst Renovation Contractor
• Your Phone Wants to Save Your Lungs (And It's Not Even Being Weird About It)
• AI Agents Just Showed Up to Cancer Research Like a Rookie Who Read the Entire Playbook
• The Tumor's Secret Weapon: How a Sneaky Enzyme Turns Your Immune System Into a No-Show
• The Prostate's Identity Crisis: When Cells Forget Who They Are
• Bulletin: Scientists Just Broke Cancer's Favorite Fence and Found Something Wild Behind It
• BREAKING: Tiny Protein Nobody Heard Of Might Be Glioblastoma's Achilles' Heel
• The Glioblastoma Symphony: When 130 Brain Cancer Experts Walk Into a Conference Room
• Look, We Need to Talk About Your Lab Mice
• Compartmentalized BCAA Metabolism in Colorectal Cancer
• When Cells Talk Behind Your Back: A New Way to Eavesdrop on Cancer's Secret Conversations
• A foundation generative model for breast ultrasound image analysis
• Dear ctDNA, We See You Now
• Senescent Obesity: The Double Agent Working Against Your Breast Health
• The Cellular Reformation: When Cancer Cells Get a New Career
• Plasmablastic Lymphoma Gets a Glow-Up: New Study Shows Dramatically Improved Survival
• What If You Could Fire the Tumor's Bodyguards?
• Weather Report: Cloudy With a Chance of Chemoresistance
• The Immune System's Turf War: How Macrophages Carve Out Battlefields Inside Lung Tumors
• Overachievers.
• The Quiet Problem With Starving Tumors of Oxygen
• The Chess Match Your Bone Marrow Didn't Know It Was Playing
• Tetraploids vs. Polyploid Giant Cells: Who's the Real Cancer Villain?
• When Lymphoma Plays Dress-Up: The Cellular Imposter That Fooled Pathologists
• The Guardian of the Genome Gets a Makeover
• Shrimp Shells vs. Breast Cancer: The Unlikely Hero Nobody Asked For
• The Triple Threat: TAS-102, Irinotecan, and Bevacizumab Take on Colorectal Cancer
• The Oncology Care Model and Medicare Payments, Utilization, and Quality
• The Childhood Leukemia That's Actually *Good* at Being Bad (And Why That Might Save Lives)
• When Your Mammogram Gets a Robot Second Opinion
• When Zombie Cells Help Cancer Spread: The Sneaky Side Hustle of Senescent Fibroblasts
• The Problem With Treating "Asian" as a Single Category in Cancer Research
• Coffee, Colonoscopies, and... Bakeoffs? How Scientists Are Racing to Find Pancreatic Cancer Sooner
• The Battlefield Inside Your Brain
• Blood Tests That Hunt Down Hidden Cancer Cells: The New Frontier in Lung Cancer Surveillance
• When Your Lungs Decide to Go Full Thanos: A Rare Cancer Meets Its Match
• The Side Hustle Nobody Expected
• The Androgen Receptor, Mapped Brick by Brick
• The Secret Society Inside Your Pancreatic Tumor
• The Hangover Pill That Might Outsmart Your Tumor
• Cultivating the Microbiome to Enhance Cancer Immunotherapy
• The Mysterious Bump That Wasn't What It Seemed
• Riding the 6 A.M. Express: How Pancreatic Cancer Built Its Own Transit System
• When Childhood Comic Books Meet Cancer-Fighting Science
• Report Card Day for a Rare Childhood Lymphoma - And It's Straight A's
• Cell-Cycle Targeted Cancer Therapy: CDK4 Inhibitors Step Into the Spotlight
• The Kitchen Sink Approach to Aggressive Prostate Cancer: When Oncologists Say "Let's Try Everything"
• Nanozyme-Mediated PROTACs Delivery for Targeted Protein Degradation and Ferroptosis Sensitization in Prostate Cancer
• When Your Gut Bacteria Sabotage Your Cancer Treatment
• When Your Immune System's Best Soldiers Get Stuck in Boot Camp
• Asciminib: The New Kid Outperforming the Old Guard in Leukemia Treatment
• The Heist Movie Playing Out Inside Your Tumors Right Now
• For a generation, we told ourselves cancer cells couldn't really do mitochondria.
• Your Heart Gets a Report Card Too: What Lymphoma Survivors Need to Know
• *Tick, tick, tick.*
• The Tiny Protein Ninjas Hiding in Your Tumors Just Got Caught on Camera
• The End of an Era: Saying Goodbye to "Let's Just Block That Protein"
• Immune Cells Are Finally Hitting the Gym, and Cervical Cancer Is Getting Crushed
• When Timing Is Everything: The Curious Case of Radiation and Immunotherapy
• The Under-50 Colon Cancer Club Nobody Wanted to Join
• The Secret Sidekick: How a Hidden RNA Is Helping Brain Tumors Outsmart Our Best Drugs
• When Cancer Plays Both Sides: The Sneaky Fusion Protein Outsmarting Our Best Drugs
• From Breakthroughs to Blueprints: Evolving Evidence and Future Directions in Relapsed and Refractory Large B-Cell Lymphoma
• When Less Chemo Might Be Just Fine: A Skeptic's Look at Pediatric Brain Tumor Treatment
• When PSA Plays Hide and Seek: Why Your Scans Matter More Than You Think
• The CD4+ T Cell Mystery: Your Immune System's Secret Power Couple
• CDK4/6 Inhibition Provides Additional Efficacy in HER2+, HR+ Breast Cancer
• The Math Problem Opening
• Your CAR T-Cells Are Getting Sabotaged - And Scientists Just Found the Fix
• In Vivo Site-Specific Engineering to Reprogram T Cells
• Immunotherapy Combinations: Oncologists Are Mixing Drugs Like Bartenders and the Results Are Getting Interesting
• CAR-T Cells: Absolute Legends in Blood Cancer, Total Tourists in Solid Tumors
• When Your Cancer's Achilles Heel Meets a One-Two Punch
• That Weird Little Organ Behind Your Sternum Might Be the Secret to Living Longer (and Beating Cancer)
• Cancer Vaccines Are Back, and They Brought mRNA Technology From the Pandemic
• Final Efficacy and Safety Data From the Phase I/II ARROW Study of Pralsetinib
• Bone Marrow Gets Its Own Bodyguard - and It's Not Who You'd Expect
• Cells Have Been Keeping Diaries, and Scientists Just Cracked the Lock
• The Machines Are Reading Pathology Slides Now, and They Are Annoyingly Good At It
• Your Immune System Has a Real Estate Problem
• When the Robot Gets an A+ But the Hospital Still Fails the Test
• First-line zolbetuximab plus mFOLFOX6 and nivolumab in unresectable CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: a phase 2 trial
• The PSMA-PET Showdown: When Copper Came for Gallium's Crown
• When Tumors Learn to Flow: The Protein Keeping Your Cells From Going Rogue
• Chewing Tobacco and Breast Cancer: The Link Nobody Was Talking About
• Your Stomach's Rebellion: Why Gastric Cancer Is Finally Meeting Its Match
• Robots Read Your Mammogram Now (And They're Weirdly Good at It)
• Tuning the Sensitivity of Mechanosensory Receptors Through Histidine Scanning
• Your Tumor's Worst Nightmare Just Got an Upgrade
• Your DNA Might Finally Save You From the PSA Roulette Wheel
• Eye Drops Made from Pig Semen: A Revolutionary Cancer Treatment?
• Same Bug, Different Story: How Bacteria Play Both Hero and Villain Inside Tumors
• When Gut Bacteria Get a Side Hustle: E. coli Turned Into Tiny Tumor-Fighting Factories
• When Your Mitochondria are More than Just Powerhouses: The Colorectal Cancer Edition
• The UK Just Screened Two Million Lungs, and the Results Are Wild
• Liquid Biopsy for Burkitt's Lymphoma: A Blood Test That Could Save Kids' Lives in Africa
• Pancreatic Cancer's Worst Nightmare: A 19-Variable Crystal Ball
• Your Body Runs the Most Sophisticated Security Operation on the Planet - and Cancer Just Hacked It
• Small Cell Lung Cancer Just Got a New Playbook - And It Involves Better Timing
• Your Leukemia Cells Just Got Evicted: Meet the Drug That Found Their Secret Hideout
• The Hormone Therapy That 6,000 Prostate Cancer Patients Helped Prove Most Men Don't Need
• The DNA Virome Varies with Human Genes and Environments
• Brain Proteins on Breast Cancer Cells: Your Immune System Was Born Ready for This Fight
• Your Thymus Has Been Quietly Running the Show This Whole Time
• When Cancer Cells Change Their Disguise Mid-Battle
• When Your Brain Tumor's DNA Plays the Odds: New Genetic Red Flags for Astrocytoma
• Estrogen Patches for Prostate Cancer? Yep, You Read That Right.
• Your Gut Bacteria Just Got a Promotion: Tiny E. coli Factories Are Pumping Out Anti-Cancer Gas
• Cancer Cells Eat Sugar Like They Are Getting Paid For It, and That Might Be Their Weakness
• Catch That Sneaky Cancer Early—The Lung Screening Revolution
• Your Immune Cells Are Tired. These Nanoparticles Brought Coffee.
• Tumor Microenvironment: A Tale of Good, Bad, and the Fibroblast Factor
• Your Immune Cells Are Running on Busted Batteries - and It's Worse Than We Thought
• Surgical approach matters for long-term lung cancer outcomes
• The World Set a 60% Survival Target for Kids With Cancer - and Then Awkwardly Realized It Might Be Too Easy
• The Protein That Plays Both Sides: How a TGFβ Vaccine Could Outsmart Pancreatic Cancer
• CRISPR Forgot Its Scissors and Became a Cancer Detector Instead
• Your Body Is Now a CAR-T Cell Factory (And It Only Takes 10 Minutes)
• When Your Cells Have a "Kill Switch" and Cancer Drugs Are Looking for the Remote
• Two Radiation Heavyweights Walked Into a Clinical Trial - and Nobody Won
• Liquid Biopsy: Finding Cancer With a Blood Draw Instead of a Scalpel
• Unpacking the Secret Life of Liver Cancer: A Deep Dive into Hepatocellular Carcinoma's Shady Origins
• Immunometabolic Gatekeeping: When Tissue Metabolism Plays the Bouncer for Tumor Immunity
• When "Stage IV" Doesn't Mean What You Think It Means
• Fungal Genes Turn T Cells Into Sugar Smugglers That Tumors Can't Rob
• Radiation Taught a Tiny Virus to Smuggle the Immune System's Most Dangerous Weapon Into Tumors
• Poop Pills and Immunotherapy: A Love Story for Stubborn Stomach Cancer
• When Cancer Learns to Swim: A Drug Trio That's Changing the Game for Brain-Lining Metastases
• 80,000 Lung Cancer Patients Walk Into a Lab...
• Unraveling the Mysteries of Mosperafenib: The New Kid on the Cancer Block
• The Undruggable Just Got Drugged: KRAS G12D Meets Its Match
• The Molecular Crumbs Cancer Leaves Behind: ctDNA and the Hunt for Minimal Residual Disease
• Should Cancer Research Pay You? The Thorny Ethics of Giving Patients Cash
• What If Your Chemo Came in a Pill Instead of a Needle?
• When Fungi and Bacteria Team Up: The Odd Couple Fueling Colorectal Cancer
• Personalized Medicine in CMML: The Tiny Bodyguard Revolution
• Smaller Cuts, Bigger Wins: Keyhole Surgery Beats the Big Slice for Lung Cancer Survival
• When Your Lymph Nodes Throw a House Party and Forget to Clean Up: The Saga of B Cell Lymphoma
• When Cancer Cells Meet Their Match: Introducing Gotistobart
• The Tumor Microenvironment: How Cancer Builds a Gated Community and Hires Its Own Security
• A multidisciplinary management approach to cervical cancer during pregnancy
• Salmonella: From Food Poisoning Villain to Cancer-Fighting Superhero
• Cancer's Worst Nightmare Just Got an Upgrade: The Rise of Antibody-Drug Conjugates
• When Your Gut Bacteria Forget How to Do Their Job, Cancer Gets Ideas